“Multisystem Inflammatory Syndrome” (MIS-C) is a type of syndrome that can occur in children after an infection. According to recent research, this syndrome, which can permanently damage the heart and tissues, can be seen in children after a possible Covid-19 infection.
What is MIS-C?
MIS-C disease occurs in children 4-6 weeks after contracting coronavirus infection. It progresses with markedly high fever, dysfunction in many organs and high inflammation markers. It is thought that autoimmune etiology may be underlying the disease with unknown cause. These children have high fever, severe abdominal pain, sore throat, vomiting, diarrhea, headache, marked fatigue, weakness, and impaired consciousness. At the same time, there are serious increases in the parameters (such as CRP, Ferritin) that we call inflammation markers in the blood values of the patients.
The disease differs from the cytokine storm seen during the coronavirus disease with some features. As everyone knows now, the number of lymphocytes in the blood decreases in coronavirus infection, but the decrease in lymphocytes is much more pronounced in MIS-C cases. In addition, the disease is similar to the ‘Kawasaki Syndrome’ but differs from it in that it is also seen in older children.