Depending on the situation, this muscle atrophy can be the following. Localized or generalized, that is, a single muscle can affect all muscles of a muscle group or all muscles of the body.

What is Atrophy?

It can be caused by an abnormality that is congenital or acquired, that is from birth, or it can be the result of an acquired disorder. Physical immobilization can cause atrophy due to a lack of muscle activity. Muscle immobility may be due, for example, to plaster placement during a fracture. This amyotrophy, sometimes referred to as muscle wasting, is benign and reversible.

Hereditary myopathies may be the cause of muscle atrophy. This is especially true for a few muscular dystrophies that are characterized by degeneration of muscle fibers.

What Causes Atrophy?

In some cases, there may be a neurological source of atrophy. Muscle atrophy is caused by damage to the nervous system. The development of muscular atrophy depends on many parameters, including the source of the muscle atrophy, the patient’s condition, and medical treatment. In some cases, muscle atrophy may increase and spread to other muscles in the body or even to the whole body. In the most severe forms, muscle atrophy can be irreversible.

Brain atrophy is a reduction in the size of the brain that affects part or all of the brain. It consists of a loss of brain mass and can lead to neurological disorders. If cerebral atrophy affects memory areas such as the hippocampus, it manifests itself in memory disorders.

This condition is not a disease, but a syndrome consisting of various symptoms. It is mostly considered an atypical form of Alzheimer’s disease. However, unlike its usual form, the memory capacities of the sick person remain intact for a long time. Other causes are possible, such as Lewy body disease or other forms of frontotemporal degeneration. PCA usually occurs before the age of 65. If this disease is not transmitted by genes, there are some rare forms involving inheritance.

What are the Types of Atrophy?

Subcortical corticosteroid atrophy refers to a decrease in brain volume. This is an age-related physiological phenomenon. In cerebral imaging of the CT or MRI type, different signs suggestive of subcortical corticosteroid atrophy are visualized.

Diffuse cortico-subcortical atrophy is defined by a reduction in the size of structures located below the cerebral cortex. This type of atrophy is a symptom of Alzheimer’s disease. It can be seen during a brain scan and helps confirm the diagnosis in dementia. The cause of this atrophy is unknown.

Fronto-parietal subcortical corticosteroid atrophy is an atrophy of brain structures predominantly in the frontal and parietal regions. In these cases, we mainly observe memory, language or speech disorders. Motor impairments can also occur in severe forms.

Corticosteroid-subcortical atrophy is largely associated with age. However, many diseases can be attributed to this, most notably Alzheimer’s disease. It occurs in other types of dementia or occurs after a brain injury, vascular accident, or brain tumor.

How to Treat Atrophy?

Unfortunately, there is no specific treatment for corticosteroid-subcortical atrophy. The management of affected subjects must first of all take care to compensate for their shortcomings, whether they have memory or behavioral problems. Anti-depressants are sometimes used to provide relief to patients. Support for those around you is also an essential part of treatment.

Corticosteroid subcortical atrophy may be seen in infants following a malformation, cerebral hypoxia, or cerebral hemorrhagic accident. The child then shows epileptic seizures and developmental problems, with a delay in learning to walk and talk. Generally, the treatments offered are the same as for Alzheimer’s disease. It can also be prescribed in rehabilitation, speech therapy, and orthoptics.

Treatment consists of treating the origin of the muscle atrophy. Drug therapy can be administered, for example, during inflammatory myopathy. Physiotherapy sessions may be recommended in case of prolonged physical inactivity.

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